| Ceftriaxone sodium Basic information |
| Product Name: | Ceftriaxone sodium |
| Synonyms: | (6R,7R)-7-[[(2Z)-2-(2-AMino-4-thiazolyl)-2-(MethoxyiMino)acetyl]aMino]-8-oxo-3-[[(1,2,5,6-tetrahydro-2-Methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]Methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid SodiuM Salt Hydrate;Ceftriaxone sodiuM sesquaterhydrate;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-, sodium salt, hydrate (2:4:7), (6R,7R)-;Ceftriaxone SodiuM Trihydrate;Ceftriaxone disodium salt hemiheptahydrate, >=98%;sodium 7-[[2-(2-amino-4-thiazolyl)-2-methoxyimino-1-oxoethyl]amino]-3-[[(2-methyl-5,6-dioxo-1H-1,2,4-triazin-3-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-, sodium salt, hydrate (2:;Ceftriaxone (sodium salt hydrate) |
| CAS: | 104376-79-6 |
| MF: | C18H16N8Na2O7S3.31/2H2O |
| MW: | 598.54 |
| EINECS: | 626-956-4 |
| Product Categories: | VESPRIN ; Antibiotics for Research and Experimental Use ; beta-Lactams (Antibiotics for Research and Experimental Use) ; Biochemistry ; API ; Antibiotic Explorer ; Intermediates & Fine Chemicals ; Pharmaceuticals ; A - KAntibiotics ; Antibacterial ; Antibiotics A to ; Antibiotics A-FAntibiotics ; Chemical Structure Class ; Interferes with Cell Wall SynthesisAntibiotics ; Mechanism of Action ; Penicillins and Cephalosporins (beta-Lactams) ; Spectrum of Activity ; Ceftriaxone ; Heterocycles ; Sulfur & Selenium Compounds |
| Mol File: | 104376-79-6.mol |
| Ceftriaxone sodium Chemical Properties |
| Melting point | 236 °C |
| alpha | D25 -165° (c = 1 in water) (calc for water-free substance) |
| refractive index | -160 ° (C=1, H2O) |
| storage temp. | 2-8°C |
| solubility | H2O: soluble50mg/mL |
| form | powder or crystals |
| pka | ~3 (COOH), 3.2 (NH3+), 4.1 (enolic OH) |
| Water Solubility | Freely soluble in water |
| InChIKey | FDRNWTJTHBSPMW-BBJOQENWSA-L |
| Safety Information |
| Hazard Codes | Xn |
| Risk Statements | 36/37/38-42/43 |
| Safety Statements | 26-36-45-37-24-22 |
| WGK Germany | 1 |
| RTECS | XI0368800 |
| HS Code | 29349990 |
| Toxicity | LD50 in male, female, mice, rats (mg/kg): 3000, 2800, 2175, 2175 i.v.; >10000 all species orally; >5000 all species s.c. (Teelman) |
| MSDS Information |
| Provider | Language |
|---|---|
| SigmaAldrich | English |
| Ceftriaxone sodium Usage And Synthesis |
| Chemical Properties | White Crystalline Solid |
| Uses | antipsychotic |
| Uses | An antibacterial, a third-generation cephalosporin. |
| Uses | A potentially useful antibacterial agent for proteomics research. |
| Brand name | Rocephin (Roche). |
| Biological Activity | β -lactam antibiotic. Displays neuroprotective activity in vivo via upregulation and increased activity of the EAAT2 glutamate transporter. |