Product Description
Product Name | Semaglutide |
CAS NO. | 910463-68-2 |
Appearance | White Powder |
Purity | 99% or customized |
Application | Drug peptides |
Description:
What is Semaglutide
?
Semaglutide
is the newest GLP-1R
agonist and was approved by the FDA as a once-weekly injection for the treatment of T2DM in late 2023. The peptide is chemically similar to liraglutide, with the inclusion of two structural modifications (
Lau, Bloch, et al., 2015
). The first is the replacement of Gly with the non-proteinogenic amino acid 2-aminoisobutyric acid (Aib) at position 2. The second is the attachment of octadecanoic diacid to the side chain of Lys-26 through a short polyethylene glycol (PEG) spacer and a γ-glutamic acid linker. The amino acid substitution renders the peptide more resistant to DPP-4 compared to liraglutide, and the presence of the 18-carbon fatty acid moiety results in a high binding affinity for serum albumin, which translates to a half-life of approximately 7 days in humans
CAS No. | Peptide Name | CAS No. | Peptide Name | CAS No. | Peptide Name |
2023788-19-2 | Tirzepatide | 37025-55-1 | Carbetocin Acetate | 148031-34-9 | Eptifibatide Acetate |
910463-68-2 | Semaglutide | 141732-76-5 | Exenatide Acetate | 128270-60-0 | Bivalirudin Trifluoroacetate |
121062-08-6 | Melanotan II Acetate | 851199-59-2 | linaclotide | 47931-85-1 | Salmon Calcitonin Acetate |
79517-01-4 | Octreotide | 214766-78-6 | Degarelix | 25126-32-3 | Sincalide (CCK-8) |
204656-20-2 | Liraglutide | 40077-57-4 | Aviptadil Acetate | 108736-35-2 | Lanreotide Acetate |
62304-98-7 | Thymosin / Thymalfasin | 107452-89-1 | Ziconotide Acetate | 103222-11-3 | Vapreotide Acetate |
76712-82-8 | Histrelin Acetate | 247062-33-5 | Abaloparatide | 307297-39-8 | Epithalon Peptide |
90779-69-4 | Atosiban Acetate | 123246-29-7 | Ganirelix acetate | 50-56-6 | Oxytocin Acetate |
52232-67-4 | Teriparatide Acetate | 17650-98-5 | Caerulein | 16679-58-6 | Desmopressin Acetate |
14636-12-5 | Terlipressin Acetate | 258818-34-7 | Larazotide | 9034-50-8 | Vasopressin Acetate |